These Jalapeño Poppers Stuffed with Brisket Mac ’n’ Cheese Are Pure Party Gold

When classic comfort food meets spicy party bites, the results are nothing short of legendary. These Smoked Brisket Mac ’n’ Cheese-Stuffed Jalapeño Poppers combine three fan favorites — melty mac, smoky brisket, and spicy jalapeños — all baked into handheld bites of pure joy. Topped with golden, buttery breadcrumbs for a perfect crunch, they’re the ultimate mashup for game day, BBQs, or anytime you want to impress with minimal effort.


Why I Love This Recipe

This one hits every note: creamy, cheesy mac; tender smoked brisket with deep flavor; spicy jalapeños to keep things exciting; and a crisp breadcrumb topper that ties it all together. It’s indulgent without being over the top, spicy but balanced, and totally customizable. Plus, they’re baked, not fried — so cleanup is a breeze.


Ingredients

  • 12 jalapeños, halved and deseeded
  • 1 cup smoked brisket, shredded
  • 1 cup macaroni noodles, cooked
  • 1 cup cheddar cheese, shredded
  • 1/2 cup cream cheese
  • 1/4 cup milk
  • 1/4 cup breadcrumbs
  • Salt and pepper, to taste
  • 1 tablespoon melted butter (for breadcrumbs)

Ingredient Swaps & Notes

  • Brisket: Leftover brisket is ideal, but you can also use pulled pork or smoked chicken.
  • Cheese: Swap cheddar for pepper jack, smoked gouda, or mozzarella for a twist.
  • Breadcrumbs: Panko adds extra crunch, or try crushed pork rinds for a low-carb version.
  • Jalapeños: For less heat, soak the halved peppers in cold water for 15 minutes before stuffing.
  • Cream Cheese: Adds creamy richness and helps the filling hold together — don’t skip it!

Instructions

  1. Preheat Oven
    Set your oven to 375°F. Line a baking sheet with parchment paper or foil for easy cleanup.
  2. Prep Jalapeños
    Slice each jalapeño in half lengthwise. Remove seeds and membranes (wear gloves if you’re spice-sensitive).
  3. Make the Filling
    In a large bowl, mix together cooked macaroni, shredded brisket, cheddar cheese, cream cheese, milk, salt, and pepper until creamy and well combined.
  4. Stuff the Peppers
    Spoon a generous amount of the mac ’n’ cheese mixture into each jalapeño half, pressing gently to fill.
  5. Breadcrumb Topping
    In a small bowl, combine breadcrumbs with melted butter. Sprinkle evenly over each stuffed pepper.
  6. Bake
    Place poppers on the prepared baking sheet and bake for 20–25 minutes, or until the jalapeños are tender and the topping is golden and bubbly.
  7. Serve
    Let cool slightly, then serve hot — maybe with some ranch or BBQ sauce on the side.

Tips for Success

  • Uniform Jalapeños: Try to pick similar-sized peppers so they cook evenly.
  • Make Ahead: Stuff the peppers up to a day in advance, then bake right before serving.
  • Spice Control: Remove all seeds for milder heat, or leave a few in if you like a fiery finish.
  • Leftover Mac: You can use leftover stovetop or baked mac ’n’ cheese in the filling for a shortcut.

Serving Suggestions & Pairings

These poppers bring the bold — so pair them with dishes and drinks that can keep up:


Storage & Leftover Tips

  • Fridge: Store leftovers in an airtight container for up to 3 days.
  • Reheat: Use an air fryer or oven at 350°F for 5–8 minutes to keep them crisp.
  • Freezer Friendly: Freeze before baking on a tray, then transfer to a bag. Bake from frozen, adding 5–10 minutes to the time.

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Final Thoughts

These Smoked Brisket Mac ’n’ Cheese-Stuffed Jalapeño Poppers are everything you want in an appetizer — creamy, spicy, crispy, and packed with bold BBQ flavor. They’re the kind of bite-sized indulgence that disappears the second you put them on the table.

Try them out, snap a pic, and tag @ChefManiac with your creation. And don’t forget to follow along for more bold, flavor-forward dishes that hit hard and taste even better.