This Jalapeño Popper Chicken Casserole Is Loaded with Cheese and Flavor

Love jalapeño poppers? Love cheesy casseroles? Then you’re in for a double win. This Ooey-Gooey Cheddar Jalapeño Popper Chicken Casserole takes all the spicy, creamy, crunchy goodness of a jalapeño popper and transforms it into a hearty baked dinner that will have everyone asking for seconds.


Why I Love This Recipe

This casserole is everything a comfort food lover dreams of—rich, creamy, melty cheddar, a little heat from the jalapeños, and that golden, buttery breadcrumb topping that gives it just the right amount of crunch. It’s incredibly easy to throw together and perfect for feeding a crowd or prepping ahead.


Ingredients

  • 1 lb boneless, skinless chicken breast, diced
  • 1 cup diced jalapeños (pickled or fresh)
  • 1 cup shredded cheddar cheese
  • 1 cup cream cheese, softened
  • 1/2 cup mayonnaise
  • 1/2 cup grated Parmesan cheese
  • 1/2 cup breadcrumbs
  • Salt and pepper to taste
  • Cooking spray

Ingredient Notes & Swaps

  • Jalapeños: Use pickled for a tangy heat or fresh for more spice. Remove seeds to control the kick.
  • Cheddar Cheese: Sharp cheddar adds bold flavor, but pepper jack or a blend works beautifully too.
  • Breadcrumbs: Panko gives extra crunch, or use crushed pork rinds for a low-carb twist.
  • Cream Cheese: Soften before mixing for a smooth, creamy texture.
  • Chicken: Rotisserie chicken makes a great time-saving sub.

Instructions

  1. Preheat oven to 375°F and spray a casserole dish with cooking spray.
  2. Mix the filling: In a large bowl, combine diced chicken, jalapeños, cheddar cheese, cream cheese, mayo, Parmesan, salt, and pepper. Stir until fully mixed.
  3. Fill the dish: Transfer mixture into the prepared casserole dish and smooth the top.
  4. Add the topping: In a small bowl, mix breadcrumbs with a little melted butter (optional). Sprinkle evenly over the casserole.
  5. Bake: Place in the oven and bake for 25–30 minutes, or until the top is golden and the chicken is cooked through.
  6. Serve hot, with fresh herbs or extra jalapeños on top if you like.

Tips for Success

  • Don’t overbake: Keep an eye on it after 25 minutes—overcooking can dry out the chicken.
  • Mix it up: Add chopped cooked bacon or a dash of hot sauce for even more flavor.
  • Make ahead: Assemble the day before and bake when ready.
  • Want it crispier? Broil for 1–2 minutes at the end for a golden crust.

Serving Suggestions & Pairings

Pair this spicy, cheesy casserole with cool, crunchy sides or dip-friendly dishes for the full experience:


Storage & Leftovers

  • Fridge: Store covered for up to 3–4 days.
  • Reheat: Warm in the oven or air fryer to restore the crunchy top.
  • Freeze: Assemble and freeze unbaked. Thaw overnight and bake as usual.

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Final Thoughts

This Ooey-Gooey Cheddar Jalapeño Popper Chicken Casserole is what happens when jalapeño poppers crash the dinner table in casserole form. Rich, creamy, spicy, and easy to make—this dish delivers big-time comfort with just the right kick.